If I miss the transfer to the airport for domestic flights, how much time before should I be at the airport?

If you miss the provided transfer to the airport for domestic flights, you can easily get there by yourself in a taxi or Uber at least 2 hours before the departure time.

These are the locations of the airports:

Bogotá: El Dorado International Airport

Medellín: José María Córdova International Airport

Cartagena: Rafael Núñez Airport